The aim of this study is to examine the relationship between mobbing and meaning of work; the predictor role of mobbing on work and meaning. The study group was 218 participants who are 162 teachers and 56 pre-service teachers in Kütahya, Turkey. The Personal Information Form included gender, age, branch, and etc., the Mobbing Scale, the Work and Meaning Inventory were used for data collection. Pearson Product Moment Correlation Analysis is applied in order to determine relationship between the variables; and multiple regression analysis is used to determine predictor roles of subdimensions of mobbing on the work and meaning. In correlation analysis, there are significant correlations between dimensions of mobbing and work-meaning. In multiple regression analysis, dimensions of mobbing have negative impact on work and meaning. The findings were discussed in relation to previous research